Another view of sexual function was presented by Rattya et al13 studying men with epilepsy (ages 18-50 years).The valproate group had enhanced sexual function and increased androstenedione levels, whereas patients taking carbamazepine or oxcarbazepine had the opposite. However, the valproate group had a higher proportion of patients with primary generalized epilepsy than the other groups. This may be an important, unexplored issue. Mattson et al6 noted different responses to progesterone in women with primary or localization-related epilepsy.
Reviewed and revised September 2004 by Steven C. Schachter, MD and Orrin Devinsky MD, epilepsy.com Editorial Board.
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