Author: BS Koppel
Support information on page: Drugs & Their Contribution to Seizures > Anxiolytics and hypnotics
| Generic name | Brand name | Metabolism |
| diazepam | Valium | CYP3A4/2C9/1A2 |
| lorazepam | Ativan | CYP3A4, GT2B7 |
| alprazolam | Xanax | CYP3A4/2C19 |
| clonazepam | Klonopin | CYP3A3/4 |
| oxazepam | Serax | |
| chlordiazepoxide | Librium | |
CYP = cytochrome P-450; GT = glucuronosyltransferase.
Adapted from: Koppel BS. Contribution of drugs and drug interactions (prescribed, over the counter, and illicit) to seizures and epilepsy. In: Ettinger AB and Devinsky O, eds. Managing epilepsy and co-existing disorders. Boston: Butterworth-Heinemann; 2002;163.
With permission from Elsevier (www.elsevier.com).
Reviewed March 2004 by Steven C. Schachter, MD, epilepsy.com Editorial Board.
