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1) Common seizures described as part of the Lennox-Gastaut Syndrome include:

  1. Simple partial seizure
  2. Myoclonic seizure
  3. Complex partial seizure
  4. Atonic seizure
  5. Secondary generalized seizure

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2) Other problems reported in Lennox-Gastaut Syndrome besides seizures include:

  1. Cardiac conditions
  2. Skin conditions
  3. Concerns regarding bone health
  4. Gastrointestinal conditions
  5. Pulmonary conditions

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3) The classic triad of Lennox-Gastaut Syndrome includes which of the following:

  1. One seizure type
  2. Slow spike in waves seen on the EEG
  3. A normal IQ
  4. A history of infantile spasms
  5. Myoclonus on awakening

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4) Which of the following can be seen on the MRI in Lennox-Gastaut Syndrome?

  1. Malformations of cortical development
  2. Tuberous sclerosis
  3. Metabolic diseases
  4. Ischemic diseases
  5. All of the above

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5) What percent of patients with Lennox-Gastaut have mental retardation reported over the course of their life?

  1. 0-25%
  2. 25-35%
  3. 36-50%
  4. 51-74%
  5. 75-100%

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6) True or False: Worsening cognition can occur in Lennox-Gastaut Syndrome even if seizures are well controlled.

  1. True
  2. False

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7) Which of the following behavioral problems are reported in Lennox-Gastaut Syndrome?

  1. Attention problems
  2. Aggression
  3. Autistic features
  4. Psychosis
  5. All of the above have been reported

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8) Which of the following seizure types are most difficult to treat in Lennox-Gastaut Syndrome?

  1. Atonic seizures
  2. Tonic seizures
  3. Absence seizures
  4. Myoclonic seizures
  5. Generalized tonic-clonic seizure

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9) Drugs with an indication to treat seizures associated with Lennox-Gastaut Syndrome include:

  1. Carbamazepine
  2. Clobazam
  3. Gabapentin
  4. Phenytoin
  5. Pregabalin

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10) Non-drug treatment of Lennox-Gastaut Syndrome include which of the following therapies:

  1. Epilepsy surgery
  2. Intravenous immunoglobulin (IVIG)
  3. Ketogenic diet
  4. Vagus nerve stimulation
  5. All of the above

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Answers

1) D - See the Sheth Presentation
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2) C - See the Sheth Presentation
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3) B - See the Jarrar Presentation
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4) E - See the Jarrar Presentation
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5) E - See the Jarrar Presentation
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6) True - See the Jarrar Presentation
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7) E - See the Jarrar Presentation
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8) B - See the Vazquez Presentation
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9) B - See the Vazquez Presentation
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10) E - See the Vazquez Presentation
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by Joseph I. Sirven, MD
Editor-in-Chief, epilepsy.com
Last Reviewed: 6/20/2012

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