Although a variety of possible pathophysiologic features have been proposed (including developmental, immunologic, and metabolic), the pathophysiology of Lennox-Gastaut syndrome (LGS) is not known.16,20,29–32 No animal models have been identified.20

Adapted from: Glauser TA and Morita DA. Lennox-Gastaut syndrome. In: Devinsky O and Westbrook LE, eds. Epilepsy and Developmental Disabilities. Boston: Butterworth-Heinemann; 2001;65–78.
With permission from Elsevier (www.elsevier.com).
Reviewed and revised May 2004 by Steven C. Schachter, MD, epilepsy.com Editorial Board.