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Update on the Diagnosis and Treatment of Epilepsy: 2006 AES Mid-Year Conference
Links to the presentations appear below.
Sponsored by:
 The American Epilepsy Society (AES), one of the oldest neurological professional organizations in the nation, with roots dating to 1898. The Society promotes research and education for professionals dedicated to the prevention, treatment, and cure of epilepsy. Membership in the Society is made up of clinicians, researchers investigating basic and clinical aspects of epilepsy, and other health-care professionals interested in seizure disorders. Members represent the pediatric and adult sides of epilepsy.
The Society is based in West Hartford, CT and holds an annual scientific meeting, offering symposia, lectures, poster presentations, and exhibitions. The meeting attracts more than 3,500 professionals from throughout the U.S. and abroad and offers excellent opportunities for networking and sharing of ideas. For more information go to www.aesnet.org or contact info@aesnet.org.
This activity is made possible by educational grants from:
Abbott Laboratories; Eisai, Inc.; GlaxoSmithKline Pharmaceuticals; Pfizer, Inc.; and UCB Pharma Inc.
Hardware and Software Requirements
PC: Pentium II or better with sound support, 16 bits color resolution, and 1024x768 pixels minimum screen resolution. Windows 95 or better, running Internet Explorer 5+ or Netscape 7.0+, Javascript enabled, and Flash 7.0+ installed.
Mac: G3 or better with sound support, 16 bits color resolution, and 1024x768 pixels minimum screen resolution. Os X, running Safari 1.0+ or Firefox 1.0+, Javascript enabled, and Flash 7.0+ installed.
Target Audience
Health-care practitioners who deal with epilepsy in their clinical practice, including neurologists, pediatricians, internists, nurses, social workers, pharmacists, psychologists, psychiatrists, and other allied health professionals.
Statement of Need
Most epilepsy patients do not see an epilepsy specialist, but receive care from general neurologists and primary care practitioners. To manage patients experiencing seizures effectively, clinicians must recognize that a patient has had a seizure, determine the seizure type, calculate the risk of seizure recurrence, and determine the best course of treatment. There are few practice guidelines or resources for clinical decision making. The roles of epileptologists and neurologists are not well defined. Patients often don’t have access to specialists.
Learning Objectives
Epilepsy: State-of-the-Art for the Practicing Clinician Plenary
- Given a patient presenting with symptoms of epilepsy, you will recognize indicators for a diagnosis of epilepsy and choose appropriate treatment options to minimize misdiagnosis.
- You will differentiate AED therapies, their contraindications, and their side effects in order to minimize adverse reactions in your patients requiring antiepileptic drug therapy.
Stopping Seizures is Not Enough Plenary
- Given patients with co-morbidities, you will formulate a treatment plan for your patients with epilepsy to maximize the therapeutic impact for their overall health and well-being.
Adult Topic Break-Out Sessions
- Given a patient with medically intractable epilepsy, you will differentiate between available non-pharmacological treatment options, including surgery, so that you can judge the effectiveness and appropriateness of these therapies for each patient.
- Given a patient requiring AED therapy, you will differentiate between age-related changes in pharmacokinetics and potential drug interactions so that patients receive individualized treatment that maximizes therapeutic benefit.
- Given the proliferation and availability of information about complementary and alternative medicine (CAM), determine the effectiveness/ineffectiveness of various CAM treatments in both adult and pediatric epileptic populations in order to address patient and caregiver concerns.
Pediatric Topic Break-Out Sessions
- Given a patient with medically intractable epilepsy, you will differentiate between available non-pharmacological treatment options including surgery so that you can judge the effectiveness and appropriateness of these therapies for each patient.
- Given a patient with epilepsy and developmental disabilities, you will determine the appropriate genetic and metabolic screening in order to arrive at a diagnosis and formulate the most effective treatment plan.
- Given a pediatric patient with epilepsy, you will construct a treatment plan that includes psychosocial and psychological approaches that minimize the effects of psychological and psychosocial comorbidities.
Professionals in Epilepsy Care (Allied Health) Topic Break-Out Sessions
- Given a patient requiring AED therapy, you will differentiate between age-related changes in pharmacokinetics and potential drug interactions so that patients receive individualized treatment that maximizes therapeutic benefit.
- Given that patients with epilepsy and their caregivers require a comprehensive approach to both medical and lifestyle management, formulate a plan to utilize self-management effectively so optimum results are achieved for the patient.
- Given that patients with epilepsy and their caregivers require a comprehensive approach to both medical and lifestyle management, formulate a plan to utilize a multidisciplinary team in the office effectively so that barriers to treatment plan implementation are minimized and optimum results are achieved for the patient.
Program Overview
The American Epilepsy Society invites you to participate in a unique educational event designed to meet your needs as a professional who cares for epilepsy patients in your clinical practice. This program consists of lectures from a live conference. Presentations are from two plenary sessions, which provide state-of-the-art updates on the diagnosis and management of epilepsy. In addition, there are videos of several break-out sessions, which cover vital topics such as choosing surgical options, avoiding drug interactions, and school issues.
Chair: Steven C. Schachter, M.D.
Full Program
User instructions: The hyperlinks listed below will send you to our partner site where you may view each of the individual presentations, including viewing the speaker, following the slides, and reading the transcript. You will notice a drop-down menu in the upper left corner of the browser window, which will allow you to customize your viewing preferences and provide an option to download copies of each session's supporting transcript and PowerPoint presentation. Use this menu if you do not immediately see the video, slides, or transcript. The double-sided arrow permits a toggle between two windows so that either the video or the slides is prominent. For Drs. Austin and Sucholeiki, a power outage during the live presentation prevented obtaining a video of the speaker; however, the audio portion, slides, and transcript are intact. During some presentations, video clips containing patients have been deleted to preserve patient confidentiality.
Epilepsy: State-of-the-Art for the Practicing Clinician Plenary
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Disorders that mimic seizures: When is it epilepsy?
Gregory L. Holmes, M.D. |
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MRIs and EEGs: When and why to order, and what do the results mean?
John S. Ebersole, M.D. |
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Panel Discussion |
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When to treat, and how to choose the first AED and beyond.
John M. Pellock, M.D
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Recognizing and minimizing side effects.
Manoj Raghavan, M.D. |
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Panel Discussion |
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Status epilepticus and other seizure emergencies: Recognition and treatment.
Michael C. Smith, M.D. |
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Epilepsy in special populations: Women, the elderly and the developmentally disabled of all ages.
L. James Willmore, M.D. |
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What to do when drugs don’t work: Brain surgery, vagus nerve stimulation and the ketogenic diet.
Elaine Wyllie, M.D. |
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Psychiatric Comorbidities: Diagnosis and treatment. Andres M. Kanner, M.D. |
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Stopping Seizures is not Enough Plenary
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Cognition and memory.
Bruce P. Hermann, Ph.D. |
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Bone health, sexual dysfunction, and other endocrine aspects.
Donna C. Bergen, M.D. |
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Panel Discussion |
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Epilepsy, sleep, and headaches.
Roy Sucholeiki, M.D. |
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Psychosocial consequences.
Joan K. Austin, D.N.S., RN |
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Adult Break-Outs
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Epilepsy surgery: When, why, and results.
Dennis Spencer, M.D. and Gabriel Lee, M.D. |
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AED Topics: Pharmacogenomics, age-related changes in pharmacokinetics, pregnancy registries, and AED-psychotropic interactions.
Barry E. Gidal, Pharm.D. and Mimi Callanan, RN, M.S.N. |
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Complementary and alternative therapies.
Steven C. Schachter, M.D. and David M. Labiner, M.D. |
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Pediatric Break-Outs
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Developmental disabilities: Genetic and metabolic screening. Which genes cause epilepsy and how?
Carl Stafstrom, M.D., Ph.D. |
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Epilepsy surgery in children.
Gary W. Mathern, M.D. |
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School issues and neuropsychological evaluation.
Michael Chez, M.D., Joan K. Austin, D.N.S., RN, and Michael Seidenberg, Ph.D. |
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Professionals in Epilepsy Care (Allied Health) Break-Outs
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Introduction to drug interactions.
Barry E. Gidal, Pharm.D |
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Self-care across the age spectrum.
Patricia Osborne Shafer, RN, M.N. |
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Role of multidisciplinary team in the management of the psychological and psychosocial consequences of epilepsy.
Mimi Callanan, RN, M.S.N., Bruce P. Hermann, Ph.D., Michael C. Smith, M.D. |
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Faculty List
Joan K. Austin, D.N.S., RN
Professor
Indiana University School of Nursing |
Donna C. Bergen, M.D.
Professor of Neurological Sciences
Rush Medical College Presbyterian |
Mimi Callanan, RN, M.S.N.
Epilepsy Clinical Nurse Specialist
Department of Neurology
Stanford University Medical Center |
Michael G. Chez, M.D.
Autism and Epilepsy Specialist
Autism and Epilepsy Specialist Services of Illinois |
John S. Ebersole, M.D.
Professor, Director of Adult Epilepsy Clinic
Department of Neurology
University of Chicago |
Barry E. Gidal, Pharm.D.
Associate Professor
School of Pharmacy-Neurology
University of Wisconsin, Madison |
Bruce Hermann, Ph.D.
Professor and Director, Mathews Laboratory of Neuropsychology
Department of Neuropsychology
University of Wisconsin |
Gregory L. Holmes, M.D.
Chief of Neurology
Neuroscience Center
Dartmouth Medical Center |
Andres M. Kanner, M.D.
Professor of Neurological Sciences
Rush Medical College |
David M. Labiner, M.D.
Director
Department of Neurology
University of Arizona |
Gabriel Lee, M.D.
Yale New Haven Hospital |
Gary W. Mathern, M.D.
Associate Professor of Neurosurgery
University of California, Los Angeles |
John M. Pellock, M.D.
Chair, Division of Child Neurology
Virginia Commonwealth University Health System |
Manoj Raghavan, M.D., Ph.D.,
Assistant Professor
Department of Neurology
Comprehensive Epilepsy Center
Medical College of Wisconsin |
Steven C. Schachter, M.D.
Professor of Neurology
Harvard Medical School
Associate Director, Clinical Research
Harvard Medical Center Osher Institute |
Michael Seidenberg, Ph.D.
Professor
Department of Psychology
Rosalind Franklin University of Medicine and Science |
Patricia Osborne Shafer, RN, M.N.
Epilepsy Clinical Nurse Specialist
Comprehensive Epilepsy Center
Beth Israel Deaconess Medical Center |
Michael C. Smith, M.D.
Director
Department of Neurological Sciences
Rush Epilepsy Center |
Dennis Spencer, M.D.
Chair, Neurosurgery, Epilepsy Surgery
School of Medicine – Neurosurgery
Yale University |
Carl E. Stafstrom, M.D., Ph.D.
Associate Professor
Chief, Division of Pediatric Neurology
Department of Neurology
University of Wisconsin, Madison Medical School |
Roy Sucholeiki, M.D.
Instructor
Neuroscience Institute
Central DuPage Hospital |
L. James Willmore, M.D.
Associate Dean and Professor of Neurology
School of Medicine
St. Louis University |
Elaine Wyllie, M.D.
Head, Pediatric Epilepsy Program
Department of Neurology
Cleveland Clinic Foundation |
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Faculty Disclosures
It is the policy of the American Epilepsy Society that all faculty participating in continuing medical education activities are expected to disclose to the program audience (1) any real or apparent conflict(s) of interest related to the content of their presentation and (2) discussions of unlabeled or unapproved uses of drugs or medical devices. The American Epilepsy Society adheres to the ACCME's Essential Areas and Policies regarding industry support of continuing medical education. Disclosure by faculty of commercial relationships, if any, and discussions of unlabeled or unapproved uses are listed below:
- Joan K. Austin, DNS, RN
has indicated that she has no real or apparent conflicts to report.
- Donna C. Bergen, M.D.
has indicated that she has received funding for Contracted Research from Schwarz Pharma, Medtronics, and Neuropace. In addition she has Company Ownership ( which may include stocks and stock options, excluding mutual funds) in Schering Plough
- Mimi Callanan, RN, M.S.N.
has indicated that she has no real or apparent conflicts to report.
- Michael G. Chez, M.D.
has indicated that he has served on the speakers bureau for Shire and Novartis, has been on the advisory board for Shire, Medpointe, and Abbott and has received consulting fees from Questcor, Accorda, and Forest Pharmaceuticals. In addition, he has done contracted research for UCB.
- John S. Ebersole, M.D.
reports that he has served on the speakers bureau and received direct honoraria from Compumedics.
- Barry E. Gidal, Pharm.D.
has indicated that he has served on the speakers bureau for
GlaxoSmithKline, UCB Pharma, and Novartis and has received consulting fees or served on the advisory board for GlaxoSmithKline and UCB Pharma. He has also performed contracted research for GlaxoSmithKline and UCB Pharma.
- Bruce Hermann, Ph.D.
has indicated that he has received consulting or advisory board fees from GlaxoSmithKline and federal research funding. He reports that his combined salary coverage is approximately 60%.
- Gregory L. Holmes, M.D.
has indicated that he has served on the speakers bureau for UCB Pharma, GlaxoSmithKline, and Novartis and has received Consulting Fees or served on an Advisory Board for UCB Pharma, GlaxoSmithKline, and Pfizer. In addition, he has performed contracted research for Johnson & Johnson, Repligen, and UCB Pharma as well as receiving federal research funding from NIH.
- Andres Kanner, M.D.
reports that he has been on a speakers bureau and advisory board and received consulting fees from GlaxoSmithKline, UCB Pharma, Ortho-McNeil, and Shire. In addition he has performed contracted research for Novartis, GlaxoSmithKline, and Eisai. He also receives federal research funding.
- David M. Labiner, M.D.
has indicated that he is on the speakers bureau for Abbott Laboratories, Cyberonics, Eisai, GlaxoSmithKline, Novartis, Ortho McNeil, Pfizer, Shire, and UCB Pharma. In addition he has received consulting fees, direct honoraria, been on an advisory board, and performed contracted research for Abbott Laboratories, Cyberonics, Eisai, GlaxoSmithKline, Novartis, Pfizer, Ortho McNeil and UCB Pharma. He also receives federal research funding from the Centers for Disease Control
- Gabriel Lee, M.D.
has indicated that he has no real or apparent conflicts to report.
- Gary W. Mathern, M.D.
has indicated that he has received consulting fees or served on the advisory board for NeuroPace and receives federal research funding.
- John Pellock, M.D.
has indicated that approximately 20% of his salary is derived from speakers, consultant, and grant activities with the following companies: Abbott Laboratories, Accorda, AstraZeneca, Aventis, Cephalon, CoSensys, Eisai, Eli Lilly & Company, GlaxoSmithKline, Marinus Pharmaceuticals, MedPointe, Novartis, Ortho McNeil Johnson & Johnson, Ovation, Pfizer, Questcor, Schwarz Pharma, UCB Pharmaceuticals, and Valeant. He also reports that approximately 5% of his salary is derived from PI or investigator on grants from Abbott, UCB, Schwarz, Valeant, OrthoMcNeil, and Ovation. In addition, he receives federal research funding. All grants, research support, consultant fees, and honoraria are paid to Virginia Commonwealth University or the physician practice plan (MCV Physicians).
- Manoj Raghavan, M.D.
has indicated that he is on the speakers bureau for GlaxoSmithkline and Novartis Pharmaceuricals.
- Steven C. Schachter, M.D.
has performed consulting work for Epilepsy.com/Epilepsy Therapy Development Project, and has received grants from the Epilepsy Research Foundation, and the American Epilepsy Society.
- Michael Seidenberg, Ph.D.
has indicated that he has no real or apparent conflicts to report.
- Patricia Osborne Shafer, RN, M.N.
has indicated that she has been on a speakers bureau, an advisory board or received consulting fees form Cyberonics and GlaxoSmithKline. She has also performed consulting work for Epilepsy.com/Epilepsy Therapy Development Project.
- Michael C. Smith, M.D.
has indicated that he has been on a speakers bureau for Abbott, GlaxoSmithKline, OrthoMcNeil, UCB Pharma, Ovation, and Eisai. He also reports serving on advisory boards or receiving consulting fees from Abbott, UCB Pharma, and Ovation Pharmaceuticals. In addition, he has received direct honoraria from Abbott, GlaxoSmithKline , OrthoMcNeil, UCB Pharma, Ovation, and Eisai. He reports that he has Company Ownership (which can include stocks and stock options, excluding mutual funds) in Elan and Ovation Pharmaceuticals.
- Dennis Spencer, M.D.
has indicated that he has no real or apparent conflicts to report.
- Carl E. Stafstrom, M.D., Ph.D.
has indicated that he has received Royalties from Patents from the Wisconsin Alumni Research Foundation.
- Roy Sucholeiki, M.D.
has indicated that he has served on the speakers bureau and received honoraria from Novartis, UCB Pharma, Abbott Laboratories, Cyberonics, and Eisai.
- L. James Willmore, M.D.
has indicated that he has no real or apparent conflicts to report.
- Elaine Wyllie, M.D.
has indicated that she has no real or apparent conflicts to report.
Disclaimer:
Opinions expressed with regard to unapproved uses of products are solely those of the faculty and are not endorsed by the American Epilepsy Society or any manufacturers of pharmaceuticals.
Special Thanks to:
The Epilepsy Therapy Development Project and www.professionals.epilepsy.com for hosting this educational activity.
11/07/2006
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