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Zonisamide
Diagnosis & Treatment > Seizure Medications > Zonisamide > Interactions of zonisamide with other medicines
 

Interactions of zonisamide with other medicines

Effects of zonisamide on other drugs
Zonisamide has no appreciable effect on the steady state plasma concentrations of other AEDs.

Effects of other drugs on zonisamide
In the presence of enzyme-inducing AEDs, zonisamide half-life decreases by approximately 50% and plasma concentration at steady state decreases.

Zonisamide is not affected by cimetidine.

AED Interaction Sheets:
Seizure drugs are often affected by drug-drug interactions. Print these informative sheets for practical help.