Children and Trileptal
The starting dose for children is usually 8 to 10 mg/kg per day, divided into two doses. Children under 8 may need a higher dose relative to weight than older children. Dosage increases should be done slowly to minimize side effects, with a target dose of 10-50 mg/kg per day.
The concentrations of the active metabolite, MHD, in children aged 6 to 18 are similar to those observed in adults, but those reported in children aged 2 to 5 are lower due to faster clearance.
If the suspension is used, it is important to stress the need to shake the bottle thoroughly immediately before measuring, and to use the measuring dropper to obtain an accurate dose.
