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Mysoline®
Diagnosis & Treatment > Seizure Medications > Mysoline® > Common side effects of Mysoline
 

Common side effects of Mysoline

The most common side effects of Mysoline are neurotoxic and dose-related. They include:

  • vertigo
  • irregular eye movements
  • nausea
  • vomiting
  • blurred or double vision
  • drowsiness
  • depression

The problems are mild to moderate and usually disappear with time or when the dose is reduced.

Some other less common side effects are:

  • loss of appetite
  • irritability
  • acne or other skin lesions
  • sexual impotency
  • decreased sexual desire
  • blood abnormalities
  • frozen shoulder

These side effects tend to occur within a week of initiation or dosage increase. In chronic therapy, they typically are noticeable 3-4 hours after a dose (associated with peak serum concentrations).

They can be lessened by:

  • reducing the total daily dosage
  • splitting the total daily dosage into more frequent doses
  • shifting more of the total daily dosage to bedtime, especially for patients with nocturnal or early-morning seizures

Patients who have just started taking Mysoline (or who have just started taking a larger amount) should be cautioned about possible sedation and to avoid activities that require full vigilance until the effects of the drug are fully apparent.