Seniors and Keppra
Patients over age 65 or 70 may have age-related reductions in kidney function that could reduce excretion and cause problems with toxicity at usual doses. Therefore, lower initial doses, longer intervals between doses, and caution in titration are required. Doses in patients with renal insufficiency should be reduced by 50%.
The lack of interactions between Keppra and other medications is an advantage over most other AEDs commonly used by seniors.
