Dosing and titration of Felbatol
In young adults, Felbatol is usually started at 600-1,200 mg per day in 3 to 4 divided doses. Every 7 to 14 days, the amount can be increased by 600 to 1,200 mg per day as required (if side effects are not troublesome), to a maximum dose of 3,600 mg day in 3-4 divided doses.
In children over 6, the starting dose is 15 mg/kg per day in 3 to 4 divided doses. The usual maintenance dose is 15-45 mg/kg per day, usually in 3 to 4 divided doses.
Refer to the Package Insert for guidance on Felbatol dosages and dosage reductions of concomitant AEDs during first 3 weeks of use.
Therapeutic levels of Felbatol have not been established.
Routine monitoring of liver and bone marrow function is recommended, but does not predict the occurrence of potentially fatal liver and bone marrow failure.
