Dosing and titration of clonazepam
Clonazepam must be introduced gradually, and a low starting dose is advisable, such as 0.5 to 1.5 mg/day, which may be taken all at once or divided into two or three doses. The dosage can be increased by 0.5 to 1 mg every 3 to 7 days. The maximum daily dose recommended is 10 mg. In a survey of epilepsy specialists, most recommended no more than 4 mg per day and usually prescribed no more than 2 mg per day.
Reviewed by Steven C. Schachter M.D., April 2005
